Rejuran Skin Booster in Korea: A Practical Guide for International Patients
동탄리쥬란 관련 정보를 찾는 분들을 위해 후즈후피부과_동탄점의 실제 공간 구성과 운영 동선을 기준으로 핵심 확인사항을 정리했습니다.

Direct answer summary
Rejuran is an injectable skin booster that uses salmon DNA fragments (polynucleotides) to support skin repair from within. In Korea, it is widely used for fine lines, enlarged pores, acne scars, and tired, dull skin. International patients usually need 3–4 sessions, spaced about 3–4 weeks apart, and can combine treatments with laser or other skin procedures depending on their skin condition.
If you are planning a medical trip to Korea, you can typically have an online consultation first, arrive for an in‑person assessment and treatment on Day 1, and return to your home country within a few days. Mild swelling and tiny bumps are common for 1–3 days, and most people return to normal activities quickly.
This guide walks you through what Rejuran is, who may consider it, how to prepare before coming to Korea, what to expect during your visit, and how to care for your skin afterward.
What is Rejuran?
Rejuran is a type of skin booster that focuses on regeneration rather than just filling or hydration. The main ingredient is polynucleotide (PN), a purified DNA fragment usually derived from salmon. These fragments are processed to be biocompatible and are injected into the superficial layer of the skin.
The goal is not to change your facial shape, but to improve overall skin quality. Over time, Rejuran may help support collagen production, improve skin elasticity, and make the skin look smoother and more refined.
Rejuran is often chosen by people who want a more natural improvement in skin texture and radiance rather than a dramatic volumizing effect.
How Rejuran works
When Rejuran is injected into the skin, the polynucleotides act as a scaffold and signal for tissue repair. They may help create a more favorable environment for fibroblasts, the cells that produce collagen and elastin.
This process is gradual. You may notice some improvement in hydration and glow within a few weeks, but the full benefit usually appears after several sessions and continues to develop over a few months.
Because it works on the skin’s foundation, Rejuran is often described as a treatment that helps the skin behave more like younger, healthier skin.
Types of Rejuran you may hear about
In Korea, you may see several versions of Rejuran. The exact names and availability can vary by clinic, but in general they include:
Rejuran classic or healer: The original version, often used for overall facial rejuvenation and fine lines.
Rejuran HB or hydrating types: These combine polynucleotides with hydrating ingredients such as hyaluronic acid to target both regeneration and moisture.
Rejuran for specific areas: Some formulations or techniques focus on the under‑eye area, neck, or acne scars.
During your consultation, the doctor will usually recommend a specific type or combination based on your skin thickness, sensitivity, and main concerns.
Who may consider Rejuran
Rejuran is usually considered by adults who want to improve skin quality rather than change their facial structure. Typical concerns include:

Fine lines and early wrinkles, especially around the eyes, cheeks, and mouth.
Rough or uneven skin texture.
Enlarged pores and oily but dehydrated skin.
Mild acne scars or shallow depressions.
Dull, tired‑looking skin after stress, sun exposure, or aging.
Neck lines or crepey skin on the neck.
It can be used on both women and men and is often recommended for people in their late 20s and above, though the exact age range depends on individual skin condition.
Who may need extra caution or avoid it
Rejuran is not suitable for everyone. You should discuss your full medical history with the clinic in Korea. In general, extra caution or alternative treatments may be needed if you:
Are pregnant or breastfeeding.
Have a history of severe allergies or anaphylaxis.
Have active skin infections, severe acne flares, or open wounds at the treatment area.
Have autoimmune skin diseases or are on certain immune‑suppressing medications.
Have a known allergy to fish or salmon derivatives.
Only a qualified medical professional who sees your skin in person can decide whether Rejuran is appropriate for you.
Expected benefits and realistic results
Rejuran is not an instant miracle or a replacement for surgery or strong lifting procedures. It is best thought of as a long‑term skin quality program.
Possible benefits include:
Smoother, more refined skin texture.
Subtle reduction in fine lines.
Improved elasticity and firmness.
More even skin tone and a healthier glow.
Less visible pores in some patients.
Softening of mild acne scars over repeated sessions.
Results are gradual and vary from person to person. Many people notice a healthier look to their skin after 2–3 sessions, but deeper wrinkles or scars may require combination treatments such as laser, radiofrequency microneedling, or other injectables.
Typical treatment plan and number of sessions
For first‑time patients, a common protocol in Korea is:
Initial series: 3–4 sessions, spaced about 3–4 weeks apart.
Maintenance: 1 session every 4–6 months, or as advised by your doctor.
If you are traveling from overseas and cannot visit frequently, your doctor may adjust the schedule, possibly combining sessions with other procedures during the same trip.
Pain, anesthesia, and comfort
Rejuran involves multiple micro‑injections across the treatment area, so some discomfort is expected. However, Korean clinics usually take several steps to reduce pain:
Topical numbing cream applied for 20–40 minutes before treatment.
Ice packs or cooling devices during or after injections.
Use of fine needles or injector devices designed for skin boosters.
Most patients describe the sensation as tolerable stinging or pricking. Sensitive areas, such as under the eyes, may feel more uncomfortable. If you have a low pain tolerance, inform the clinic in advance so they can plan appropriate measures.

Common side effects and downtime
Because Rejuran is injected into the superficial dermis, tiny bumps (often called “embossing”) are very common right after the procedure. Other typical short‑term effects include:
Redness and pinpoint marks at injection sites.
Mild swelling, especially under the eyes or on the cheeks.
Occasional small bruises.
These usually improve within 1–3 days. Some people feel comfortable returning to work the next day, while others prefer to schedule the treatment before a weekend or holiday.
Serious side effects are rare but can include infection, prolonged swelling, nodules, or allergic reactions. Choosing an experienced medical team and following aftercare instructions reduce these risks.
Online consultation before your trip
If you live abroad, an online consultation is an efficient first step before planning your visit to Korea.
Most clinics will ask you for:
Clear photos of your face or treatment area in natural lighting from the front and both sides.
Information about your age, main concerns, and what you hope to improve.
Details about your medical history, including allergies, medications, previous procedures, and any chronic illnesses.
Your travel dates or approximate schedule.
Based on this information, the clinic can:
Suggest whether Rejuran is likely to help your concerns.
Recommend a tentative treatment plan and number of sessions.
Explain possible combination treatments, such as laser or LDM ultrasound for skin barrier support.
Provide an estimated budget and time required for each visit.
This pre‑visit communication helps you decide whether to proceed and how long you should stay in Korea.
How to prepare before coming to Korea
To make your treatment smoother and safer, consider the following steps before your trip:
Avoid blood‑thinning supplements and medications if your doctor allows it. These include high‑dose fish oil, vitamin E, certain herbal products, aspirin, and other blood thinners. Never stop prescribed medication without your own doctor’s approval.
Limit alcohol intake for several days before treatment to reduce bruising risk.
Avoid strong skin treatments like deep chemical peels or aggressive lasers for at least 2–4 weeks before Rejuran, unless your doctor advises a specific combination plan.
Prepare a list of all skincare products and medications you use to show the clinic.
Plan your travel schedule so that you have at least 1–2 free days after treatment in case of swelling or bruising.
What to expect on your treatment day in Korea
On the day of your appointment, the process usually follows these steps:
1. Registration and consultation
You will fill out medical questionnaires and consent forms. The doctor will examine your skin, discuss your goals, and confirm whether Rejuran is appropriate.
You can ask about expected results, possible side effects, and whether other treatments should be done before or after Rejuran.
2. Photography and cleansing
Staff may take standardized photos for your medical record. Your face or treatment area will be cleansed to remove makeup, sunscreen, and impurities.
3. Numbing and preparation
Topical anesthetic cream is applied and left on for about 20–40 minutes. This step is important for comfort, especially if a large area is treated.
After numbing, the cream is removed and the skin is disinfected.
4. Injection procedure
The doctor injects Rejuran into the superficial layer of the skin using a fine needle or an injector device. You may feel small pricks and pressure.
Tiny bumps will appear across the treated area. This is a normal sign that the product has been placed in the correct layer.
The actual injection time is usually 10–30 minutes, depending on the area and technique.

5. Cooling and calming care
After injections, cooling packs, soothing masks, or gentle devices such as LDM ultrasound or low‑energy lasers may be used to calm the skin and support recovery.
6. Aftercare instructions and payment
The clinic will explain how to care for your skin at home, what to avoid, and when to schedule your next session. You will then proceed with payment and appointment booking.
Typical visit timeline for international patients
If you are visiting Korea specifically for Rejuran, a sample schedule might look like this:
Short trip for a single session
Day 1: Arrival in Korea, clinic visit, consultation, and first Rejuran session.
Day 2–3: Light sightseeing or rest. Mild swelling or bumps may still be visible.
Day 3–4: Return flight home once you feel comfortable.
Extended plan for multiple sessions
If you can stay longer or visit Korea several times a year, your doctor may suggest:
First trip: 1–2 sessions, spaced 3–4 weeks apart if your stay allows.
Follow‑up trips: Maintenance sessions every few months, possibly combined with lasers or other treatments.
If you cannot travel often, discuss with the clinic how to coordinate Rejuran sessions with treatments available in your home country.
Aftercare: what to do and what to avoid
Good aftercare helps your skin recover and supports better results. Clinics may give slightly different instructions, but common recommendations include:
Skincare
Use gentle, fragrance‑free cleansers and moisturizers.
Apply a soothing cream or barrier‑repair product recommended by the clinic.
Use a broad‑spectrum sunscreen (SPF 30 or higher) every day, even if you stay indoors.
Avoid harsh exfoliants, retinoids, strong acids, and scrubs for at least 5–7 days or until your doctor allows.
Activities
Avoid saunas, hot baths, and intense exercise that causes heavy sweating for 1–3 days.
Do not massage or press the treated area unless your doctor specifically instructs you to.
Try not to sleep face‑down on the first night.
Lifestyle
Limit alcohol and smoking, as they may impair skin healing.
Stay hydrated and get enough sleep to support regeneration.
When to contact the clinic
Contact the clinic or seek medical help if you notice:
Severe or rapidly worsening redness, swelling, or pain.
Pus, warmth, or fever suggesting infection.
Hard nodules that do not improve over time.
Any other symptoms that worry you.
Frequently asked questions
How long do Rejuran results last?
After the initial series of 3–4 sessions, many patients enjoy improved skin quality for several months. Maintenance sessions every 4–6 months are often recommended to sustain the effect. However, individual longevity varies depending on age, lifestyle, and skin condition.
Is Rejuran the same as filler?
No. Traditional fillers, such as hyaluronic acid fillers, are mainly used to add volume or contour specific areas like the cheeks, chin, or lips. Rejuran is a skin booster focused on regeneration and texture. It does not aim to change facial shape but to improve the quality of the skin itself.
Can Rejuran be combined with other treatments?
Yes. In Korea, it is often combined with:
Laser treatments for pigmentation, redness, or pores.
LDM ultrasound or similar devices for skin barrier and hydration.
Radiofrequency microneedling for tightening and scars.
Other injectables such as botulinum toxin or fillers, depending on your needs.

The order and timing of these procedures must be planned carefully by your doctor to avoid over‑treating the skin.
Is there a lot of bruising?
Because Rejuran involves many small injections, there is always a chance of bruising. Some people have only tiny red dots that fade quickly, while others may develop small purple marks that take about 7–10 days to disappear. Avoiding blood‑thinning medications and supplements (with your own doctor’s approval) can help reduce this risk.
Will I look swollen or unnatural?
Right after the procedure, you may look bumpy and slightly swollen due to the micro‑deposits of product. This usually settles within 1–3 days. Rejuran does not create the kind of volume associated with overfilled faces; its aim is subtle improvement in texture and radiance.
How soon can I wear makeup?
Most clinics advise waiting at least 24 hours before applying makeup to reduce the risk of irritation or infection. After that, you can usually use light, non‑comedogenic products. Always follow the specific instructions given by your doctor.
Can I do Rejuran just once?
You can have a single session, but the full benefit is usually seen after a series of treatments. One session may give a temporary boost in hydration and glow, but for longer‑lasting changes in texture and elasticity, repeated sessions are recommended.
Is it safe for darker skin tones?
Rejuran does not rely on strong heat or peeling, so it is generally considered suitable for a wide range of skin tones. However, people with darker skin may be more prone to post‑inflammatory hyperpigmentation from any needle‑based or energy‑based procedure. An experienced doctor will adjust the overall treatment plan to minimize this risk.
How do I choose a clinic in Korea?
When selecting a clinic, consider:
Experience with Rejuran and other skin boosters.
Clear communication in English or your preferred language.
Before‑and‑after photos of similar cases, if available.
Transparent explanation of costs, number of sessions, and realistic expectations.
Responsiveness to your questions during online consultation.
It is also helpful to check whether the clinic can coordinate your treatment schedule with your travel dates and provide support if you have concerns after returning home.
Soft call to action
If you are considering Rejuran in Korea and want to know whether it suits your skin concerns, an online consultation is the best first step. By sharing clear photos, your medical history, and your travel schedule, you can receive a personalized treatment plan and a realistic idea of the time and budget required.
Reach out to a trusted Korean skin clinic, ask your questions openly, and take your time to decide. With careful planning and proper aftercare, Rejuran can be a valuable part of a long‑term strategy to keep your skin looking healthier, smoother, and more radiant during and after your visit to Korea.
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